Detalhe da pesquisa
1.
Baricitinib treatment resolves lower-airway macrophage inflammation and neutrophil recruitment in SARS-CoV-2-infected rhesus macaques.
Cell
; 184(2): 460-475.e21, 2021 01 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-33278358
2.
SOX11 is a novel binding partner and endogenous inhibitor of SAMHD1 ara-CTPase activity in mantle cell lymphoma.
Blood
; 143(19): 1953-1964, 2024 May 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-38237141
3.
Light-strand bias and enriched zones of embedded ribonucleotides are associated with DNA replication and transcription in the human-mitochondrial genome.
Nucleic Acids Res
; 52(3): 1207-1225, 2024 Feb 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-38117983
4.
Vpx requires active cellular dNTP biosynthesis to effectively counteract the anti-lentivirus activity of SAMHD1 in macrophages.
J Biol Chem
; 299(8): 104984, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37390988
5.
Synthesis and evaluation of highly potent HBV capsid assembly modulators (CAMs).
Bioorg Chem
; 141: 106923, 2023 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37871391
6.
Targeting SAMHD1 with hydroxyurea in first-line cytarabine-based therapy of newly diagnosed acute myeloid leukaemia: Results from the HEAT-AML trial.
J Intern Med
; 292(6): 925-940, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35934913
7.
Novel Hepatitis B Virus Capsid Assembly Modulator Induces Potent Antiviral Responses In Vitro and in Humanized Mice.
Antimicrob Agents Chemother
; 64(2)2020 01 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-31712213
8.
Template-assisted synthesis of adenine-mutagenized cDNA by a retroelement protein complex.
Nucleic Acids Res
; 46(18): 9711-9725, 2018 10 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30007279
9.
Nucleoside Analogs with Antiviral Activity against Yellow Fever Virus.
Antimicrob Agents Chemother
; 63(9)2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31262759
10.
Baricitinib reverses HIV-associated neurocognitive disorders in a SCID mouse model and reservoir seeding in vitro.
J Neuroinflammation
; 16(1): 182, 2019 Sep 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-31561750
11.
Characterization of ß-d-N4-Hydroxycytidine as a Novel Inhibitor of Chikungunya Virus.
Antimicrob Agents Chemother
; 61(4)2017 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28137799
12.
Pharmacokinetics and Placental Transfer of Elvitegravir, Dolutegravir, and Other Antiretrovirals during Pregnancy.
Antimicrob Agents Chemother
; 61(6)2017 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28348149
13.
The Janus kinase inhibitor ruxolitinib reduces HIV replication in human macrophages and ameliorates HIV encephalitis in a murine model.
Neurobiol Dis
; 92(Pt B): 137-43, 2016 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-26851503
14.
Biochemical Characterization of the Active Anti-Hepatitis C Virus Metabolites of 2,6-Diaminopurine Ribonucleoside Prodrug Compared to Sofosbuvir and BMS-986094.
Antimicrob Agents Chemother
; 60(8): 4659-69, 2016 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27216050
15.
Erratum for Amblard et al., "Novel Hepatitis B Virus Capsid Assembly Modulator Induces Potent Antiviral Responses In Vitro and in Humanized Mice".
Antimicrob Agents Chemother
; 64(9)2020 08 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-32819965
16.
Design, synthesis and evaluation of novel anti-HCV molecules that deliver intracellularly three highly potent NS5A inhibitors.
Bioorg Med Chem Lett
; 25(17): 3711-5, 2015 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26099532
17.
dNTP pool modulation dynamics by SAMHD1 protein in monocyte-derived macrophages.
Retrovirology
; 11: 63, 2014 Aug 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-25158827
18.
Randomized, double-blind, multicenter safety and efficacy study of rifalazil compared with azithromycin for treatment of uncomplicated genital Chlamydia trachomatis infection in women.
Antimicrob Agents Chemother
; 58(7): 4014-9, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-24798277
19.
Enhanced antiretroviral therapy in rhesus macaques improves RT-SHIV viral decay kinetics.
Antimicrob Agents Chemother
; 58(7): 3927-33, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-24777106
20.
Stably-Inverted Apical-Out Human Upper Airway Organoids for SARS-CoV-2 Infection and Therapeutic Testing.
bioRxiv
; 2024 Jan 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-38260306